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The researchers observed low or very low confidence in evidence for reduced pain intensity after treatment with tolperisone, aceclofenac plus tizanidine, pregabalin (mean differences, −26.1, −26.1, and −24.7, respectively), and 14 other medicines versus placebo. Data were reviewed from 98 randomized controlled trials (15,134 participants), which included 69 medicines and combinations. Wewege, from the University of New South Wales in Sydney, and colleagues conducted a systematic review and network meta-analysis to assess the comparative effectiveness and safety of analgesic medicines for acute nonspecific low back pain. MONDAY, Ma(HealthDay News) - For patients with acute low back pain, the comparative effectiveness and safety of analgesic medications is unclear, according to a systematic review and meta-analysis published online March 22 in The BMJ. Editors and writers make all efforts to clarify any financial ties behind the studies on which we report. All of our articles are chosen independent of any financial interests. HeathDay is committed to maintaining the highest possible levels of impartial editorial standards in the content that we present on our website. Any known potential conflicts of interest associated with a study or source are made clear to the reader.Įditorial and Fact-Checking Policy for more detail.Įditorial and Fact-Checking Policy HealthDay Editorial Commitment.Each article includes a link or reference to the original source.Peer-reviewed journals or issued from independent and respected medical associations, academic groups and governmental organizations. Unless otherwise noted, all articles focusing on new research are based on studies published in.All articles are edited and checked for factual accuracy by our.Team of industry experts to ensure accuracy. Our syndicated news content is completely independent of any financial interests, is based solely on industry-respected sources and the latest scientific research, and is carefully fact-checked by a HealthDay operates under the strictest editorial standards.
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